Amy Nicole (Denny) O'Keefe, 42, of Brownsburg, IN returned to God on July 15th 2025 after a private and brave battle with breast cancer. Amy was born in Seymour, IN on Nov. 12th 1982 to Brenda and Mark Denny. Amy was a graduate of Pike HS in 2001 and held a Bachelor's of Fine Arts from Herron School of Art and Design. Amy met her husband John while working at Connor's Pub in Broad Ripple, and they had an instant connection. They were married on August, 2 2018. On June 5th, 2021 they were blessed with their son, Russell to whom she was a wonderful mother. Amy was a talented and humble artist, those closest to her were fortunate to be gifted with her whimsical creations which will now keep her spirit alive and present. Beauty was a central theme in her life, and she couldn't resist sparkle and color, making her a uniquely bright spot in her loved ones lives.  Anyone who knew Amy will attest that she was truly a charming, caring, and beautiful human inside and out. Surviving are John O'Keefe (Husband), Russell O'Keefe (Son), Brenda Denny and Gary Bruner (Mother/Stepfather), Bryan Denny and Cindy Rodolfo (Brother and Sister-in-Law). In lieu of flowers, please consider honoring Amy's creative spirit by supporting the arts in your community. Visit a local gallery, take an art class, donate to an arts education program, or simply make something beautiful. Amy believed in the power of art to heal, inspire, and connect — and your act of creativity will carry her light forward.

A funeral mass will be held on Saturday July 19, 2025 at 1:30 P.M. in Mary Queen of Peace Catholic Church.  Burial will follow in New Winchester Cemetery. No visitation will be observed.